Morton’s Neuroma Revisited

Thank you all so much for your comments and support. I have received a lot of feedback and fantastic questions about Morton’s neuromas (MN) and your problems with diagnosis and treatment of such. This area of the foot can indeed be terrifically confusing and difficult to diagnose. I want to help you all as much as I can with this conundrum, and I would love to answer each and every one of you individually, but I just can’t and shouldn’t in this setting.
If you have been labeled with the diagnosis of a Morton’s neuroma and various treatments are not working so well, maybe you don’t have a Morton’s neuroma.
The MN diagnosis is made way too often. Why? Here are some misconceptions that surround the dreaded Morton’s neuroma that can lead us astray:
MN’s are really common. Actually they are not common, especially a 2nd web space MN (15%, I think almost ZERO percent). Even 3rd web space MN are not common. If your doc is indicating a 2nd web space MN, question it and consider the much more common 2nd MTP synovitis (inflammation of the central ball joint). If they are thinking 1st or 4th web space, RUN.
MN diagnosis is SEXY. We docs just got to make that diagnosis. “You have a Morton’s neuroma”. It has teeth. It sounds so definitive and sure. It is like a golf ball set up on a tee just waiting to be shanked.
MN’s are easy to diagnose. Actually, they are not easy to diagnose. I have done this for 27 years and now more than ever, I am now even more cautious and I respect making this diagnosis more than ever. It is actually a diagnosis of exclusion. This means that I rule out the other possibilities to the best of my ability before making the call of a MN. Too many good docs jump right to this diagnosis. It has to be the last diagnosis, and even then I am often not as sure as I would like to be normally.
“You have a Mulder’s click”. This is a physical finding that is rarely helpful, but boy, do love it.
The MRI and more recently, ultrasound have not helped matters either. In fact, those who rely on these tests are trying to increasingly make a claim regarding their diagnostic prowess, which is not true. Stick to old fashion history and exam.
MN may be all your doctor knows.
Basically, central forefoot (2nd, 3rd, 4th metatarsal head region, not 1st or 5th) pain that starts in an otherwise normal foot can be divvied up into four basic diagnoses the great majority of the time. There are several more diagnoses that are uncommon and frankly, outliers that are not discussed here such as Freiberg’s infraction, inflammatory arthritis (rheumatoid), etc. Here are the names and the diagnostic criteria, according to the AO. Keep in mind that the majority of these can be diagnosed by history alone and an MRI or an ultra sound is generally not needed in any of these. In fact, they are a waste of time and money. If your doc is quick to say they need an MRI to make the diagnosis consider another route. I’m not sayin’, I’m just sayin’. Exam is important, but only to support and confirm the history. By the way, no matter what you think or hear, none of these ever have a history of actual causative acute trauma. If you have a history of trauma and you have one of these I would say True-True-Unrelated. Finally I am not discussing treatment. The treatment of each of these is clearcut as long as one is confident in the diagnosis, which what this is about. Intractable plantar keratosis (IPK) or plantar corn or callus
Generally older, 50 yo plus, but can be any adult
Pain is on the bottom
Insidious slow onset, present for some time
Visible seed, small tight callus that is exquisitely tender to touch.
No swelling
You would have to be brain dead to miss this one.
Pain only with weight bearing
Worse on barefoot, better in shoes
When it comes to trauma, this one could be the exception. If there is bonafide past or remote trauma to your foot/metatarsal or previous surgery that leads you to have a residual unevenness to the weight bearing surface of your metatarsals, then you could develop an IPK form that.
X-rays negative
Can be confused with a plantar wart.
Metatarsal neck stress fracture
Ages
Military recruits, boot camp, “march fracture”
Distance runners, any age, training error
50+ female>>male
Recent rapid onset
Recent rise in activity level, especially number of steps! Normal activity to many more steps per day, vacation, new exercise program, etc. Or lower activity as in being down from prolonged inactivity, i.e.illness, heading back to your normal activity level. Jumping out of the back of a pick up truck and breaking your metatarsal is an acute fracture, not a stress fracture, and is different.
Pain on top of foot
Swelling top of foot
Usually 2nd metatarsal, next to big toe metatarsal
Pain with weight bearing, with or with out shoes
X-rays negative in first 21 days, then new reparative bone formation is seen and sometimes the fracture is seen.
Morton’s neuroma
Adults, peak age 40’s thru 50’s.
Insidious onset, often years.
Unlike all the others, at first and often even later, the location of the pain can be vague; can’t pinpoint. Can be frustrating for patient and doctor alike. However, knowing this can ultimately be helpful if used correctly.
Pain mostly on bottom.
Can take a while to get started with standing/walking.
Worse in confining shoes, better in sandals or barefoot.
NO SWELLING..............EVER. Whoops, caps lock on again.
Can feel swollen however. Numbness can feel like swelling. Remember the last time you got home from the dentist and you looked in the mirror because you were sure that your tongue was hanging out of your mouth only to find out all was well. I rest my case.
There can be a sensation of actual, perceptible numbness between the two affected toe which border the neuroma. This sensation or finding by your doc is extremely variable and unreliable. It’s presence or absence really means nothing. I ignore it basically except to support my other findings.
Mulder’s click is a useless finding. It’s absence means nothing. While I do dismiss it, a Mulder’s click may be supportive if when performed it exactly recreates your pain.
3rd web...85-90%, 2nd web 10-15%, 1st or 4th web.......not.
These are two things that get my attention and often have meaning, but only supportive with other findings and history:
feeling of folded sock bottom of foot
urge to take off shoes and rub foot. Does not matter whether you actually ever do it, it is just the urge part.
Second MTP synovitis (AKA, capsulitis, pre-dislocation syndrome)
Majority in specific demographic, 55 +/- yo female
Not mentioned as differential diagnosis on Mayo or WebMD sites, but capsulitis is right there on Wikipedia.
By and far the most common of these four diagnoses
Primarily 2nd metatarsal. Infrequently the 3rd.
Insidious onset, few days to weeks.
Swelling top and bottom often, but not always.
Painful “lump” or “rock” under ball of foot. Pain on bottom.
Worse on hard floor barefoot, better on carpet or cushioned shoes.
Sometimes there is the perception of some form of trauma, but any trauma is just the “straw that broke the camels back” phenomenon. For instance dancing at a wedding in heels to get it started. But here is something you MUST know; it was going to start eventually anyway because it is a result of:
mostly these occur as a result of calves that are too tight which places more pressure on the forefoot/metatarsal heads. This represents a more recent change and why this is happening now and not before.
In a very small part due to the anatomy because the 2nd metatarsal is the most prominent in almost all of us. This has been your anatomy forever and has not changed. Your doctor might refer to your 2nd metatarsal that is “too long”, but it has been that length all your life. Seriously, it isn’t as if your metatarsal magically grew longer recently. Now, refer back to calves.
Transfer metatarsalgia secondary to a bunion. Often blamed, but the calves that are too tight are the larger reason this is going on at this point in your life.
When this problem is left untreated, eventually a hammertoe will develop if the swelling is allowed to persist. Hey, here is a novel idea. The great majority of isolated 2nd and/or 3rd hammertoes result from MTP synovitis which comes from calves that are too tight, which is almost completely preventable as long as you stretch your calves.
Often the inflammation from the 2nd MTP synovitis can irritate the adjacent 2nd web space nerve causing neuritis, which is a secondary thing and not a Morton’s neuroma. If you are reading this, chances are you fit in one of these four groups. Certainly you’ve gotten loads of information from the stranger on the bus next to you, or your nosey neighbor (everybody is an expert), or from the internet, or even your doctor. Again, the mere fact that you are reading this means things probably aren’t going so well. No matter what you have heard from these random sources statistically your problem is second MTP synovitis, and not a Morton’s neuroma.
Donna on August 10, 2024 at 5:03 am
Hi Angry Orthopod,
This was a really interesting read! I do think I have MN and have been diagnosed as such. And they said I have equinus, which virtually no-one seems to have heard of! I was wondering if I might be able to send you my ultrasound and diagnostic info from the clinic I went to to see if you can help advise! I’m pretty desperate at this stage as nothing is working.
Many thanks,
Donna
AngryOrthopod on August 11, 2024 at 11:10 am
Hi Donna,
Thanks for reaching out. I had to have some extra coffee because your request got me seriously riled up. My answer here is for everyone BTW.…
Jennifer Warner on July 24, 2019 at 1:25 pm
Thank you for everything you do. I have recently been diagnosed with a Morton’s neuroma (by two different podiatrists and was wondering if a slant board would be helpful for calf stretching. I travel for work (by car) and don’t always have access to a step. Something like this… StrongTek Foot Rest Under Desk, Slant Board, Foot Stool for Work at Office and Home (Footrest for Desk), Anti Slip Design, Ankle Stretching, 4 Positions Calve Stretch Wedge (300LB Capacity)
https://www.amazon.com/dp/B06XR6GJ3S/ref=cm_sw_r_cp_api_i_0pjoDbYRP31ZHReply
Jennifer Warner on July 24, 2019 at 1:53 pm
Here are my symptoms…Worse first thing in the morning.Stairs hurt, more when going down. Shooting pain in between 2nd and 3rd toes. Sneakers…
John on December 15, 2023 at 4:54 am
I got pain in my right foot one year ago after i did standing calf raises in a new gym on a machine I never tried before. Had some pain during the exercises and after my foot felt swollen around 3/4 metatarsal heads. Never had any foot issues before this. For the next 2 weeks the pain came and went, but then disappeared. When i tried training again, the pain came back. Since then I stopped doing everthing that provoked pain, but the pain has just gotten worst. After a couples of month my left foot started as well, but never the same intensity as my right. Today the pain is so bad…
Bob on February 2, 2022 at 12:22 am
Thanks so much for the wonderful site! Here’s my situation: About six months ago I began to have pain in my right foot. Lateral side around midfoot. I surf, and had been more sedentary since covid, so figured it was general aches and pains of new use. Pain has come and gone, but past couple months much worse. But in new spots! Baby toe feels like I slammed it in a door (I didn’t), and when I wake up in the morning, or after sitting for a while, my foot is incredibly stiff and painful when I first walk. Assumed it was a whacked out PF but doc says MN. Pain on palpation…
Mu on January 31, 2022 at 11:34 pm
Hi!
Oh wow!!!!What a treasure did I find????I’ve had Morton since I was 20. I’m 60 now.I wish I could walk barefoot constantly outside…Anyway, I’m going to stretch. I have no other problems in my cute little feet. This Morton crap is horrible to bear! Cannot wear the nice little shoes here or there because I already know I’m going to suffer!I put pads in each left shoes so it stretches my feet but forget a small high heel to look taller 🙁Anyway, thank you very much for your site! You are a doctor at my own heart. If that is English…
aoeditor on February 7, 2022 at 3:43 pm
Hi there Mu,